GATOR2 complex protein MIOS (MIOS)
Homo sapiens — UniProt Q9NXC5
Data last refreshed: (UniProt release unknown)
Key facts
GATOR2 complex protein MIOS (MIOS) is a protein from Homo sapiens identified by UniProt accession Q9NXC5, 875 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q9NXC5; gene symbol MIOS.
- Organism: Homo sapiens.
- Length: 875 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, generalized anxiety disorder and pulmonary arterial hypertension.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | GATOR2 complex protein MIOS |
|---|---|
| UniProt accession | Q9NXC5 |
| Gene | MIOS |
| Organism | Homo sapiens |
| Length | 875 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- generalized anxiety disorder · score 0.09
- pulmonary arterial hypertension · score 0.07
- DNA methylation · score 0.04
- Ventricular arrhythmia · score 0.01
- cancer · score 0.01
- acute quadriplegic myopathy · score 0.01
- Sepsis · score 0.00
- multiple myeloma · score 0.00
- Dilated cardiomyopathy · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NXC5-F1 | alphafold | PREDICTED | 82.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NXC5.
Amino-acid sequence (875 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MIOS?
The strongest Open Targets associations for MIOS are neurodegenerative disease, generalized anxiety disorder, pulmonary arterial hypertension, DNA methylation and Ventricular arrhythmia.
How long is the MIOS protein?
The Homo sapiens MIOS protein (UniProt Q9NXC5) is 875 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NXC5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NXC5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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