Pre-mRNA-splicing factor CWC25 homolog (CWC25)
Homo sapiens — UniProt Q9NXE8
Data last refreshed: (UniProt release unknown)
Key facts
Pre-mRNA-splicing factor CWC25 homolog (CWC25) is a protein from Homo sapiens identified by UniProt accession Q9NXE8, 425 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.
- UniProt accession: Q9NXE8; gene symbol CWC25.
- Organism: Homo sapiens.
- Length: 425 amino acids.
- Top disease associations (Open Targets): body height, waist-hip ratio and BMI-adjusted waist-hip ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Pre-mRNA-splicing factor CWC25 homolog |
|---|---|
| UniProt accession | Q9NXE8 |
| Gene | CWC25 |
| Organism | Homo sapiens |
| Length | 425 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (6)
Diseases linked to this target (Open Targets).
- body height · score 0.04
- waist-hip ratio · score 0.04
- BMI-adjusted waist-hip ratio · score 0.04
- intraocular pressure measurement · score 0.04
- cancer · score 0.01
- triple-negative breast cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NXE8-F1 | alphafold | PREDICTED | 65.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NXE8.
Amino-acid sequence (425 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CWC25?
The strongest Open Targets associations for CWC25 are body height, waist-hip ratio, BMI-adjusted waist-hip ratio, intraocular pressure measurement and cancer.
How long is the CWC25 protein?
The Homo sapiens CWC25 protein (UniProt Q9NXE8) is 425 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NXE8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NXE8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.