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Testis-expressed protein 10 (TEX10)

Homo sapiens — UniProt Q9NXF1

Gene: TEX10Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Testis-expressed protein 10 (TEX10) is a protein from Homo sapiens identified by UniProt accession Q9NXF1, 929 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

  • UniProt accession: Q9NXF1; gene symbol TEX10.
  • Organism: Homo sapiens.
  • Length: 929 amino acids.
  • Top disease associations (Open Targets): body mass index, lean body mass and body fat percentage.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameTestis-expressed protein 10
UniProt accessionQ9NXF1
GeneTEX10
OrganismHomo sapiens
Length929 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (44)

Diseases linked to this target (Open Targets).

  • body mass index · score 0.36
  • lean body mass · score 0.34
  • body fat percentage · score 0.31
  • fat body mass · score 0.30
  • body weight · score 0.29
  • waist-hip ratio · score 0.24
  • body height · score 0.22
  • serum alanine aminotransferase measurement · score 0.21
  • sex hormone-binding globulin measurement · score 0.21
  • high density lipoprotein cholesterol measurement · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NXF1-F1alphafoldPREDICTED80.05—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NXF1.

Amino-acid sequence (929 residues)

MTKKRKRQHD FQKVKLKVGK KKPKLQNATP TNFKTKTIHL PEQLKEDGTL PTNNRKLNIK DLLSQMHHYN AGVKQSALLG LKDLLSQYPF IIDAHLSNIL SEVTAVFTDK DANVRLAAVQ LLQFLAPKIR AEQISPFFPL VSAHLSSAMT HITEGIQEDS LKVLDILLEQ YPALITGRSS ILLKNFVELI SHQQLSKGLI NRDRSQSWIL SVNPNRRLTS QQWRLKVLVR LSKFLQALAD GSSRLRESEG LQEQKENPHA TSNSIFINWK EHANDQQHIQ VYENGGSQPN VSSQFRLRYL VGGLSGVDEG LSSTENLKGF IEIIIPLLIE CWVEAVPPQL ATPVGNGIER EPLQVMQQVL NIISLLWKLS KQQDETHKLE SWLRKNYLID FKHHFMSRFP YVLKEITKHK RKEPNKSIKH CTVLSNNIDH LLLNLTLSDI MVSLANASTL QKDCSWIEMI RKFVTETLED GSRLNSKQLN RLLGVSWRLM QIQPNREDTE TLIKAVYTLY QQRGLILPVR TLLLKFFSKI YQTEELRSCR FRYRSKVLSR WLAGLPLQLA HLGSRNPELS TQLIDIIHTA AARANKELLK SLQATALRIY DPQEGAVVVL PADSQQRLVQ LVYFLPSLPA DLLSRLSRCC IMGRLSSSLA AMLIGILHMR SSFSGWKYSA KDWLMSDVDY FSFLFSTLTG FSKEELTWLQ SLRGVPHVIQ TQLSPVLLYL TDLDQFLHHW DVTEAVFHSL LVIPARSQNF DILQSAISKH LVGLTVIPDS TAGCVFGVIC KLLDHTCVVS ETLLPFLASC CYSLLYFLLT IEKGEAEHLR KRDKLWGVCV SILALLPRVL RLMLQSLRVN RVGPEELPVV GQLLRLLLQH APLRTHMLTN AILVQQIIKN ITTLKSGSVQ EQWLTDLHYC FNVYITGHPQ GPSALATVY

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with TEX10?

The strongest Open Targets associations for TEX10 are body mass index, lean body mass, body fat percentage, fat body mass and body weight.

How long is the TEX10 protein?

The Homo sapiens TEX10 protein (UniProt Q9NXF1) is 929 amino acids long.

Browse: Targets: T · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NXF1
GeneTEX10
OrganismHomo sapiens
Length929
Binders0
Diseases44
View on UniProt