DDB1- and CUL4-associated factor 16 (DCAF16)
Homo sapiens — UniProt Q9NXF7
Data last refreshed: (UniProt release unknown)
Key facts
DDB1- and CUL4-associated factor 16 (DCAF16) is a protein from Homo sapiens identified by UniProt accession Q9NXF7, 216 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.
- UniProt accession: Q9NXF7; gene symbol DCAF16.
- Organism: Homo sapiens.
- Length: 216 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body height and BMI-adjusted hip circumference.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DDB1- and CUL4-associated factor 16 |
|---|---|
| UniProt accession | Q9NXF7 |
| Gene | DCAF16 |
| Organism | Homo sapiens |
| Length | 216 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (79)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- body height · score 0.30
- BMI-adjusted hip circumference · score 0.16
- genetic disorder · score 0.12
- testosterone measurement · score 0.11
- body mass index · score 0.10
- platelet count · score 0.10
- type 2 diabetes mellitus · score 0.09
- hypertension · score 0.09
- intelligence · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NXF7-F1 | alphafold | PREDICTED | 38.20 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NXF7.
Amino-acid sequence (216 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DCAF16?
The strongest Open Targets associations for DCAF16 are neurodegenerative disease, body height, BMI-adjusted hip circumference, genetic disorder and testosterone measurement.
How long is the DCAF16 protein?
The Homo sapiens DCAF16 protein (UniProt Q9NXF7) is 216 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NXF7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NXF7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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