Palmitoyltransferase ZDHHC7 (ZDHHC7)
Homo sapiens — UniProt Q9NXF8
Data last refreshed: (UniProt release unknown)
Key facts
Palmitoyltransferase ZDHHC7 (ZDHHC7) is a protein from Homo sapiens identified by UniProt accession Q9NXF8, 308 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q9NXF8; gene symbol ZDHHC7.
- Organism: Homo sapiens.
- Length: 308 amino acids.
- Top disease associations (Open Targets): body height, BMI-adjusted waist circumference and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Palmitoyltransferase ZDHHC7 |
|---|---|
| UniProt accession | Q9NXF8 |
| Gene | ZDHHC7 |
| Organism | Homo sapiens |
| Length | 308 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- body height · score 0.31
- BMI-adjusted waist circumference · score 0.27
- cancer · score 0.08
- hepatocellular carcinoma · score 0.07
- progressive supranuclear palsy · score 0.04
- neoplasm · score 0.03
- monocyte count · score 0.02
- cardiac hypertrophy · score 0.01
- non-alcoholic steatohepatitis · score 0.01
- Dilated cardiomyopathy · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NXF8-F1 | alphafold | PREDICTED | 83.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NXF8.
Amino-acid sequence (308 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZDHHC7?
The strongest Open Targets associations for ZDHHC7 are body height, BMI-adjusted waist circumference, cancer, hepatocellular carcinoma and progressive supranuclear palsy.
How long is the ZDHHC7 protein?
The Homo sapiens ZDHHC7 protein (UniProt Q9NXF8) is 308 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NXF8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NXF8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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