Membrane progestin receptor gamma (PAQR5)
Homo sapiens — UniProt Q9NXK6
Data last refreshed: (UniProt release unknown)
Key facts
Membrane progestin receptor gamma (PAQR5) is a protein from Homo sapiens identified by UniProt accession Q9NXK6, 330 residues long. MolForge cross-references it against 0 known binders and 89 disease associations.
- UniProt accession: Q9NXK6; gene symbol PAQR5.
- Organism: Homo sapiens.
- Length: 330 amino acids.
- Top disease associations (Open Targets): calcium measurement, basophil count and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Membrane progestin receptor gamma |
|---|---|
| UniProt accession | Q9NXK6 |
| Gene | PAQR5 |
| Organism | Homo sapiens |
| Length | 330 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (89)
Diseases linked to this target (Open Targets).
- calcium measurement · score 0.46
- basophil count · score 0.37
- appendicular lean mass · score 0.33
- systolic blood pressure · score 0.33
- basophil percentage of leukocytes · score 0.30
- hypertension · score 0.30
- heel bone mineral density · score 0.30
- lymphocyte count · score 0.29
- blood protein measurement · score 0.15
- blood pressure · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NXK6-F1 | alphafold | PREDICTED | 92.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NXK6.
Amino-acid sequence (330 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PAQR5?
The strongest Open Targets associations for PAQR5 are calcium measurement, basophil count, appendicular lean mass, systolic blood pressure and basophil percentage of leukocytes.
How long is the PAQR5 protein?
The Homo sapiens PAQR5 protein (UniProt Q9NXK6) is 330 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NXK6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NXK6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.