SID1 transmembrane family member 1 (SIDT1)
Homo sapiens — UniProt Q9NXL6
Data last refreshed: (UniProt release unknown)
Key facts
SID1 transmembrane family member 1 (SIDT1) is a protein from Homo sapiens identified by UniProt accession Q9NXL6, 827 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.
- UniProt accession: Q9NXL6; gene symbol SIDT1.
- Organism: Homo sapiens.
- Length: 827 amino acids.
- Top disease associations (Open Targets): mean platelet volume, prostate carcinoma and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SID1 transmembrane family member 1 |
|---|---|
| UniProt accession | Q9NXL6 |
| Gene | SIDT1 |
| Organism | Homo sapiens |
| Length | 827 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (61)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.45
- prostate carcinoma · score 0.44
- platelet count · score 0.42
- calcium measurement · score 0.42
- type 2 diabetes mellitus · score 0.34
- cortical surface area measurement · score 0.30
- blood phosphate measurement · score 0.30
- brain measurement · score 0.24
- cortical thickness · score 0.18
- BMI-adjusted waist-hip ratio · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NXL6-F1 | alphafold | PREDICTED | 80.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NXL6.
Amino-acid sequence (827 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SIDT1?
The strongest Open Targets associations for SIDT1 are mean platelet volume, prostate carcinoma, platelet count, calcium measurement and type 2 diabetes mellitus.
How long is the SIDT1 protein?
The Homo sapiens SIDT1 protein (UniProt Q9NXL6) is 827 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NXL6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NXL6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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