DNA helicase MCM9 (MCM9)
Homo sapiens — UniProt Q9NXL9
Data last refreshed: (UniProt release unknown)
Key facts
DNA helicase MCM9 (MCM9) is a protein from Homo sapiens identified by UniProt accession Q9NXL9, 1143 residues long. MolForge cross-references it against 0 known binders and 186 disease associations.
- UniProt accession: Q9NXL9; gene symbol MCM9.
- Organism: Homo sapiens.
- Length: 1143 amino acids.
- Top disease associations (Open Targets): 46,XX gonadal dysgenesis, neurodegenerative disease and testosterone measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DNA helicase MCM9 |
|---|---|
| UniProt accession | Q9NXL9 |
| Gene | MCM9 |
| Organism | Homo sapiens |
| Length | 1143 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (186)
Diseases linked to this target (Open Targets).
- 46,XX gonadal dysgenesis · score 0.65
- neurodegenerative disease · score 0.52
- testosterone measurement · score 0.43
- self reported educational attainment · score 0.43
- premature ovarian failure 1 · score 0.42
- mean platelet volume · score 0.41
- electrocardiography · score 0.38
- erythrocyte count · score 0.36
- platelet count · score 0.32
- multiple sclerosis · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NXL9-F1 | alphafold | PREDICTED | 61.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NXL9.
Amino-acid sequence (1143 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MCM9?
The strongest Open Targets associations for MCM9 are 46,XX gonadal dysgenesis, neurodegenerative disease, testosterone measurement, self reported educational attainment and premature ovarian failure 1.
How long is the MCM9 protein?
The Homo sapiens MCM9 protein (UniProt Q9NXL9) is 1143 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NXL9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NXL9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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