BRISC and BRCA1-A complex member 2 (BABAM2)
Homo sapiens — UniProt Q9NXR7
Data last refreshed: (UniProt release unknown)
Key facts
BRISC and BRCA1-A complex member 2 (BABAM2) is a protein from Homo sapiens identified by UniProt accession Q9NXR7, 383 residues long. MolForge cross-references it against 0 known binders and 114 disease associations.
- UniProt accession: Q9NXR7; gene symbol BABAM2.
- Organism: Homo sapiens.
- Length: 383 amino acids.
- Top disease associations (Open Targets): refractive error measurement, age at menopause and triglyceride measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BRISC and BRCA1-A complex member 2 |
|---|---|
| UniProt accession | Q9NXR7 |
| Gene | BABAM2 |
| Organism | Homo sapiens |
| Length | 383 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (114)
Diseases linked to this target (Open Targets).
- refractive error measurement · score 0.33
- age at menopause · score 0.29
- triglyceride measurement · score 0.27
- hair shape measurement · score 0.27
- intraocular pressure measurement · score 0.25
- balding measurement · score 0.25
- response to tricyclic antidepressant · score 0.22
- RR interval · score 0.22
- glomerular filtration rate · score 0.22
- BMI-adjusted hip circumference · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NXR7-F1 | alphafold | PREDICTED | 92.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NXR7.
Amino-acid sequence (383 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BABAM2?
The strongest Open Targets associations for BABAM2 are refractive error measurement, age at menopause, triglyceride measurement, hair shape measurement and intraocular pressure measurement.
How long is the BABAM2 protein?
The Homo sapiens BABAM2 protein (UniProt Q9NXR7) is 383 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NXR7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NXR7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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