Glutaminyl-peptide cyclotransferase-like protein (QPCTL)
Homo sapiens — UniProt Q9NXS2
Data last refreshed: (UniProt release unknown)
Key facts
Glutaminyl-peptide cyclotransferase-like protein (QPCTL) is a protein from Homo sapiens identified by UniProt accession Q9NXS2, 382 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q9NXS2; gene symbol QPCTL.
- Organism: Homo sapiens.
- Length: 382 amino acids.
- Top disease associations (Open Targets): blood protein measurement, glucose measurement and coronary artery disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glutaminyl-peptide cyclotransferase-like protein |
|---|---|
| UniProt accession | Q9NXS2 |
| Gene | QPCTL |
| Organism | Homo sapiens |
| Length | 382 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.24
- glucose measurement · score 0.21
- coronary artery disease · score 0.18
- body mass index · score 0.14
- testosterone measurement · score 0.12
- waist-hip ratio · score 0.11
- left atrial volume measurement · score 0.11
- diet measurement · score 0.10
- platelet count · score 0.09
- waist circumference · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NXS2-F1 | alphafold | PREDICTED | 89.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NXS2.
Amino-acid sequence (382 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with QPCTL?
The strongest Open Targets associations for QPCTL are blood protein measurement, glucose measurement, coronary artery disease, body mass index and testosterone measurement.
How long is the QPCTL protein?
The Homo sapiens QPCTL protein (UniProt Q9NXS2) is 382 amino acids long.
Browse: Targets: Q · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NXS2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NXS2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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