ADP-ribosylation factor-like protein 15 (ARL15)
Homo sapiens — UniProt Q9NXU5
Data last refreshed: (UniProt release unknown)
Key facts
ADP-ribosylation factor-like protein 15 (ARL15) is a protein from Homo sapiens identified by UniProt accession Q9NXU5, 204 residues long. MolForge cross-references it against 0 known binders and 150 disease associations.
- UniProt accession: Q9NXU5; gene symbol ARL15.
- Organism: Homo sapiens.
- Length: 204 amino acids.
- Top disease associations (Open Targets): reticulocyte count, type 2 diabetes mellitus and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ADP-ribosylation factor-like protein 15 |
|---|---|
| UniProt accession | Q9NXU5 |
| Gene | ARL15 |
| Organism | Homo sapiens |
| Length | 204 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (150)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.53
- type 2 diabetes mellitus · score 0.50
- Red cell distribution width · score 0.48
- reticulocyte measurement · score 0.47
- sex hormone-binding globulin measurement · score 0.46
- vital capacity · score 0.45
- high density lipoprotein cholesterol measurement · score 0.45
- systolic blood pressure · score 0.44
- creatinine measurement · score 0.44
- appendicular lean mass · score 0.44
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NXU5-F1 | alphafold | PREDICTED | 88.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NXU5.
Amino-acid sequence (204 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ARL15?
The strongest Open Targets associations for ARL15 are reticulocyte count, type 2 diabetes mellitus, Red cell distribution width, reticulocyte measurement and sex hormone-binding globulin measurement.
How long is the ARL15 protein?
The Homo sapiens ARL15 protein (UniProt Q9NXU5) is 204 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NXU5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NXU5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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