CDKN2A-interacting protein (CDKN2AIP)
Homo sapiens — UniProt Q9NXV6
Data last refreshed: (UniProt release unknown)
Key facts
CDKN2A-interacting protein (CDKN2AIP) is a protein from Homo sapiens identified by UniProt accession Q9NXV6, 580 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q9NXV6; gene symbol CDKN2AIP.
- Organism: Homo sapiens.
- Length: 580 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Familial prostate cancer and prostate carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CDKN2A-interacting protein |
|---|---|
| UniProt accession | Q9NXV6 |
| Gene | CDKN2AIP |
| Organism | Homo sapiens |
| Length | 580 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- Familial prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
- neoplasm · score 0.08
- hepatocellular carcinoma · score 0.05
- laryngotracheoesophageal cleft · score 0.05
- testicular seminoma · score 0.04
- Abnormality of the urinary system · score 0.02
- response to radiation · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NXV6-F1 | alphafold | PREDICTED | 61.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NXV6.
Amino-acid sequence (580 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CDKN2AIP?
The strongest Open Targets associations for CDKN2AIP are neurodegenerative disease, Familial prostate cancer, prostate carcinoma, prostate cancer and neoplasm.
How long is the CDKN2AIP protein?
The Homo sapiens CDKN2AIP protein (UniProt Q9NXV6) is 580 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NXV6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NXV6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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