C-type lectin domain family 5 member A (CLEC5A)
Homo sapiens — UniProt Q9NY25
Data last refreshed: (UniProt release unknown)
Key facts
C-type lectin domain family 5 member A (CLEC5A) is a protein from Homo sapiens identified by UniProt accession Q9NY25, 188 residues long. MolForge cross-references it against 0 known binders and 148 disease associations.
- UniProt accession: Q9NY25; gene symbol CLEC5A.
- Organism: Homo sapiens.
- Length: 188 amino acids.
- Top disease associations (Open Targets): blood protein measurement, neoplasm and infect.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | C-type lectin domain family 5 member A |
|---|---|
| UniProt accession | Q9NY25 |
| Gene | CLEC5A |
| Organism | Homo sapiens |
| Length | 188 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (148)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.17
- neoplasm · score 0.09
- infect · score 0.09
- infection · score 0.09
- cancer · score 0.08
- rheumatoid arthritis · score 0.08
- glioblastoma multiforme · score 0.08
- dengue disease · score 0.08
- Rheumatoid arthritis · score 0.08
- glioblastoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NY25-F1 | alphafold | PREDICTED | 85.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NY25.
Amino-acid sequence (188 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLEC5A?
The strongest Open Targets associations for CLEC5A are blood protein measurement, neoplasm, infect, infection and cancer.
How long is the CLEC5A protein?
The Homo sapiens CLEC5A protein (UniProt Q9NY25) is 188 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NY25 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NY25 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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