Zinc transporter ZIP1 (SLC39A1)
Homo sapiens — UniProt Q9NY26
Data last refreshed: (UniProt release unknown)
Key facts
Zinc transporter ZIP1 (SLC39A1) is a protein from Homo sapiens identified by UniProt accession Q9NY26, 324 residues long. MolForge cross-references it against 0 known binders and 90 disease associations.
- UniProt accession: Q9NY26; gene symbol SLC39A1.
- Organism: Homo sapiens.
- Length: 324 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): neurodegenerative disease, blood protein measurement and diet measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc transporter ZIP1 |
|---|---|
| UniProt accession | Q9NY26 |
| Gene | SLC39A1 |
| Organism | Homo sapiens |
| Length | 324 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (90)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- blood protein measurement · score 0.14
- diet measurement · score 0.13
- neoplasm · score 0.10
- mathematical ability · score 0.09
- hepatocellular carcinoma · score 0.08
- protein measurement · score 0.08
- cortical thickness · score 0.07
- number of children ever born measurement · score 0.07
- cancer · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NY26-F1 | alphafold | PREDICTED | 80.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NY26.
Amino-acid sequence (324 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC39A1?
The strongest Open Targets associations for SLC39A1 are neurodegenerative disease, blood protein measurement, diet measurement, neoplasm and mathematical ability.
How long is the SLC39A1 protein?
The Homo sapiens SLC39A1 protein (UniProt Q9NY26) is 324 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NY26 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NY26 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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