Serine/threonine-protein phosphatase 4 regulatory subunit 2 (PPP4R2)
Homo sapiens — UniProt Q9NY27
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein phosphatase 4 regulatory subunit 2 (PPP4R2) is a protein from Homo sapiens identified by UniProt accession Q9NY27, 417 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q9NY27; gene symbol PPP4R2.
- Organism: Homo sapiens.
- Length: 417 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, breast adenocarcinoma and Abnormality of refraction.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein phosphatase 4 regulatory subunit 2 |
|---|---|
| UniProt accession | Q9NY27 |
| Gene | PPP4R2 |
| Organism | Homo sapiens |
| Length | 417 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- breast adenocarcinoma · score 0.25
- Abnormality of refraction · score 0.19
- monocyte count · score 0.19
- refractive error · score 0.14
- body height · score 0.14
- glioblastoma multiforme · score 0.12
- pulse pressure measurement · score 0.11
- attention deficit hyperactivity disorder · score 0.08
- acute myeloid leukemia · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NY27-F1 | alphafold | PREDICTED | 62.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NY27.
Amino-acid sequence (417 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PPP4R2?
The strongest Open Targets associations for PPP4R2 are neurodegenerative disease, breast adenocarcinoma, Abnormality of refraction, monocyte count and refractive error.
How long is the PPP4R2 protein?
The Homo sapiens PPP4R2 protein (UniProt Q9NY27) is 417 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NY27 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NY27 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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