Probable polypeptide N-acetylgalactosaminyltransferase 8 (GALNT8)
Homo sapiens — UniProt Q9NY28
Data last refreshed: (UniProt release unknown)
Key facts
Probable polypeptide N-acetylgalactosaminyltransferase 8 (GALNT8) is a protein from Homo sapiens identified by UniProt accession Q9NY28, 637 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q9NY28; gene symbol GALNT8.
- Organism: Homo sapiens.
- Length: 637 amino acids.
- Top disease associations (Open Targets): electrocardiography, Atypical behavior and Macrocephaly.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Probable polypeptide N-acetylgalactosaminyltransferase 8 |
|---|---|
| UniProt accession | Q9NY28 |
| Gene | GALNT8 |
| Organism | Homo sapiens |
| Length | 637 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- electrocardiography · score 0.41
- Atypical behavior · score 0.27
- Macrocephaly · score 0.27
- epicanthal fold · score 0.27
- Short philtrum · score 0.27
- Hypermetropia · score 0.27
- Epicanthus · score 0.27
- flatfoot · score 0.27
- Seizure · score 0.27
- Focal-onset seizure · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NY28-F1 | alphafold | PREDICTED | 86.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NY28.
Amino-acid sequence (637 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GALNT8?
The strongest Open Targets associations for GALNT8 are electrocardiography, Atypical behavior, Macrocephaly, epicanthal fold and Short philtrum.
How long is the GALNT8 protein?
The Homo sapiens GALNT8 protein (UniProt Q9NY28) is 637 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NY28 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NY28 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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