Claudin domain-containing protein 1 (CLDND1)
Homo sapiens — UniProt Q9NY35
Data last refreshed: (UniProt release unknown)
Key facts
Claudin domain-containing protein 1 (CLDND1) is a protein from Homo sapiens identified by UniProt accession Q9NY35, 253 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q9NY35; gene symbol CLDND1.
- Organism: Homo sapiens.
- Length: 253 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Stroke and breast cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Claudin domain-containing protein 1 |
|---|---|
| UniProt accession | Q9NY35 |
| Gene | CLDND1 |
| Organism | Homo sapiens |
| Length | 253 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.29
- Stroke · score 0.02
- breast cancer · score 0.02
- cancer · score 0.01
- neoplasm · score 0.01
- cerebrovascular disorder · score 0.01
- Down syndrome · score 0.00
- astrocytoma · score 0.00
- Rheumatoid arthritis · score 0.00
- schizophrenia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NY35-F1 | alphafold | PREDICTED | 87.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NY35.
Amino-acid sequence (253 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLDND1?
The strongest Open Targets associations for CLDND1 are neurodegenerative disease, Stroke, breast cancer, cancer and neoplasm.
How long is the CLDND1 protein?
The Homo sapiens CLDND1 protein (UniProt Q9NY35) is 253 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NY35 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NY35 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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