Solute carrier family 2, facilitated glucose transporter member 8 (SLC2A8)
Homo sapiens — UniProt Q9NY64
Data last refreshed: (UniProt release unknown)
Key facts
Solute carrier family 2, facilitated glucose transporter member 8 (SLC2A8) is a protein from Homo sapiens identified by UniProt accession Q9NY64, 477 residues long. MolForge cross-references it against 0 known binders and 107 disease associations.
- UniProt accession: Q9NY64; gene symbol SLC2A8.
- Organism: Homo sapiens.
- Length: 477 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): neurodegenerative disease, glioblastoma multiforme and cognitive decline measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Solute carrier family 2, facilitated glucose transporter member 8 |
|---|---|
| UniProt accession | Q9NY64 |
| Gene | SLC2A8 |
| Organism | Homo sapiens |
| Length | 477 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (107)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.34
- glioblastoma multiforme · score 0.23
- cognitive decline measurement · score 0.21
- lung adenocarcinoma · score 0.18
- azoospermia · score 0.07
- male infertility with teratozoospermia due to single gene mutation · score 0.06
- platelet count · score 0.05
- familial sick sinus syndrome · score 0.05
- Brugada syndrome · score 0.05
- spermatogenic failure 7 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NY64-F1 | alphafold | PREDICTED | 85.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NY64.
Amino-acid sequence (477 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC2A8?
The strongest Open Targets associations for SLC2A8 are neurodegenerative disease, glioblastoma multiforme, cognitive decline measurement, lung adenocarcinoma and azoospermia.
How long is the SLC2A8 protein?
The Homo sapiens SLC2A8 protein (UniProt Q9NY64) is 477 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NY64 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NY64 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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