Ewing's tumor-associated antigen 1 (ETAA1)
Homo sapiens — UniProt Q9NY74
Data last refreshed: (UniProt release unknown)
Key facts
Ewing's tumor-associated antigen 1 (ETAA1) is a protein from Homo sapiens identified by UniProt accession Q9NY74, 926 residues long. MolForge cross-references it against 0 known binders and 146 disease associations.
- UniProt accession: Q9NY74; gene symbol ETAA1.
- Organism: Homo sapiens.
- Length: 926 amino acids.
- Top disease associations (Open Targets): pancreatic carcinoma, age at menopause and BMI-adjusted waist-hip ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ewing's tumor-associated antigen 1 |
|---|---|
| UniProt accession | Q9NY74 |
| Gene | ETAA1 |
| Organism | Homo sapiens |
| Length | 926 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (146)
Diseases linked to this target (Open Targets).
- pancreatic carcinoma · score 0.39
- age at menopause · score 0.36
- BMI-adjusted waist-hip ratio · score 0.36
- waist-hip ratio · score 0.33
- hair shape measurement · score 0.33
- PHF-tau measurement · score 0.32
- balding measurement · score 0.32
- type 2 diabetes mellitus · score 0.31
- FEV/FVC ratio · score 0.30
- BMI-adjusted waist circumference · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NY74-F1 | alphafold | PREDICTED | 49.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NY74.
Amino-acid sequence (926 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ETAA1?
The strongest Open Targets associations for ETAA1 are pancreatic carcinoma, age at menopause, BMI-adjusted waist-hip ratio, waist-hip ratio and hair shape measurement.
How long is the ETAA1 protein?
The Homo sapiens ETAA1 protein (UniProt Q9NY74) is 926 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NY74 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NY74 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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