Sperm protein associated with the nucleus on the X chromosome C (SPANXC)
Homo sapiens — UniProt Q9NY87
Data last refreshed: (UniProt release unknown)
Key facts
Sperm protein associated with the nucleus on the X chromosome C (SPANXC) is a protein from Homo sapiens identified by UniProt accession Q9NY87, 97 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q9NY87; gene symbol SPANXC.
- Organism: Homo sapiens.
- Length: 97 amino acids.
- Top disease associations (Open Targets): blood protein measurement, hepatocellular carcinoma and melanoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sperm protein associated with the nucleus on the X chromosome C |
|---|---|
| UniProt accession | Q9NY87 |
| Gene | SPANXC |
| Organism | Homo sapiens |
| Length | 97 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.21
- hepatocellular carcinoma · score 0.02
- melanoma · score 0.02
- cancer · score 0.01
- neoplasm · score 0.01
- Cirrhosis · score 0.00
- metastatic melanoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NY87-F1 | alphafold | PREDICTED | 68.05 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NY87.
Amino-acid sequence (97 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPANXC?
The strongest Open Targets associations for SPANXC are blood protein measurement, hepatocellular carcinoma, melanoma, cancer and neoplasm.
How long is the SPANXC protein?
The Homo sapiens SPANXC protein (UniProt Q9NY87) is 97 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NY87 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NY87 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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