Probable glucose sensor protein SLC5A4 (SLC5A4)
Homo sapiens — UniProt Q9NY91
Data last refreshed: (UniProt release unknown)
Key facts
Probable glucose sensor protein SLC5A4 (SLC5A4) is a protein from Homo sapiens identified by UniProt accession Q9NY91, 659 residues long. MolForge cross-references it against 2 known binders and 73 disease associations.
- UniProt accession: Q9NY91; gene symbol SLC5A4.
- Organism: Homo sapiens.
- Length: 659 amino acids.
- Top disease associations (Open Targets): adolescent idiopathic scoliosis, Crohn's disease and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Probable glucose sensor protein SLC5A4 |
|---|---|
| UniProt accession | Q9NY91 |
| Gene | SLC5A4 |
| Organism | Homo sapiens |
| Length | 659 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (73)
Diseases linked to this target (Open Targets).
- adolescent idiopathic scoliosis · score 0.06
- Crohn's disease · score 0.03
- Red cell distribution width · score 0.03
- anti-chlamydia trachomatis antibody measurement · score 0.02
- erythrocyte count · score 0.02
- diastolic blood pressure · score 0.02
- HbA1c measurement · score 0.02
- inflammatory bowel disease · score 0.02
- attention deficit hyperactivity disorder · score 0.01
- lung adenocarcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NY91-F1 | alphafold | PREDICTED | 85.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NY91.
Amino-acid sequence (659 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC5A4?
The strongest Open Targets associations for SLC5A4 are adolescent idiopathic scoliosis, Crohn's disease, Red cell distribution width, anti-chlamydia trachomatis antibody measurement and erythrocyte count.
How long is the SLC5A4 protein?
The Homo sapiens SLC5A4 protein (UniProt Q9NY91) is 659 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NY91 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NY91 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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