Probable ATP-dependent RNA helicase DDX56 (DDX56)
Homo sapiens — UniProt Q9NY93
Data last refreshed: (UniProt release unknown)
Key facts
Probable ATP-dependent RNA helicase DDX56 (DDX56) is a protein from Homo sapiens identified by UniProt accession Q9NY93, 547 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.
- UniProt accession: Q9NY93; gene symbol DDX56.
- Organism: Homo sapiens.
- Length: 547 amino acids.
- Top disease associations (Open Targets): low density lipoprotein cholesterol measurement, ulcerative colitis and sleep duration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Probable ATP-dependent RNA helicase DDX56 |
|---|---|
| UniProt accession | Q9NY93 |
| Gene | DDX56 |
| Organism | Homo sapiens |
| Length | 547 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (64)
Diseases linked to this target (Open Targets).
- low density lipoprotein cholesterol measurement · score 0.30
- ulcerative colitis · score 0.22
- sleep duration · score 0.21
- alcohol drinking · score 0.21
- alcohol consumption measurement · score 0.18
- total cholesterol measurement · score 0.16
- neurodegenerative disease · score 0.16
- physical activity · score 0.15
- adolescent idiopathic scoliosis · score 0.14
- hepatocellular carcinoma · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NY93-F1 | alphafold | PREDICTED | 79.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NY93.
Amino-acid sequence (547 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DDX56?
The strongest Open Targets associations for DDX56 are low density lipoprotein cholesterol measurement, ulcerative colitis, sleep duration, alcohol drinking and alcohol consumption measurement.
How long is the DDX56 protein?
The Homo sapiens DDX56 protein (UniProt Q9NY93) is 547 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NY93 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NY93 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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