About N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 (B3GNT2) is a protein
from Homo sapiens identified by UniProt accession
Q9NY97, 397 residues long.
MolForge cross-references it against 0 known binders and
100 disease associations.
Target properties
| Protein name | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 |
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| UniProt accession | Q9NY97 |
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| Gene | B3GNT2 |
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| Organism | Homo sapiens |
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| Length | 397 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (100)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.42
- erythrocyte count · score 0.40
- testosterone measurement · score 0.40
- Red cell distribution width · score 0.40
- ankylosing spondylitis · score 0.38
- mean corpuscular hemoglobin concentration · score 0.37
- mean reticulocyte volume · score 0.36
- mean corpuscular hemoglobin · score 0.35
- psoriasis · score 0.34
- lymphocyte count · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NY97-F1 | alphafold | PREDICTED | 91.04 | — |
Amino-acid sequence (397 residues)
MSVGRRRIKL LGILMMANVF IYFIMEVSKS SSQEKNGKGE VIIPKEKFWK ISTPPEAYWN REQEKLNRQY NPILSMLTNQ TGEAGRLSNI SHLNYCEPDL RVTSVVTGFN NLPDRFKDFL LYLRCRNYSL LIDQPDKCAK KPFLLLAIKS LTPHFARRQA IRESWGQESN AGNQTVVRVF LLGQTPPEDN HPDLSDMLKF ESEKHQDILM WNYRDTFFNL SLKEVLFLRW VSTSCPDTEF VFKGDDDVFV NTHHILNYLN SLSKTKAKDL FIGDVIHNAG PHRDKKLKYY IPEVVYSGLY PPYAGGGGFL YSGHLALRLY HITDQVHLYP IDDVYTGMCL QKLGLVPEKH KGFRTFDIEE KNKNNICSYV DLMLVHSRKP QEMIDIWSQL QSAHLKC
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