N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 (B3GNT2)
Homo sapiens — UniProt Q9NY97
Data last refreshed: (UniProt release unknown)
Key facts
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 (B3GNT2) is a protein from Homo sapiens identified by UniProt accession Q9NY97, 397 residues long. MolForge cross-references it against 0 known binders and 100 disease associations.
- UniProt accession: Q9NY97; gene symbol B3GNT2.
- Organism: Homo sapiens.
- Length: 397 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, erythrocyte count and testosterone measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 |
|---|---|
| UniProt accession | Q9NY97 |
| Gene | B3GNT2 |
| Organism | Homo sapiens |
| Length | 397 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (100)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.42
- erythrocyte count · score 0.40
- testosterone measurement · score 0.40
- Red cell distribution width · score 0.40
- ankylosing spondylitis · score 0.38
- mean corpuscular hemoglobin concentration · score 0.37
- mean reticulocyte volume · score 0.36
- mean corpuscular hemoglobin · score 0.35
- psoriasis · score 0.34
- lymphocyte count · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NY97-F1 | alphafold | PREDICTED | 91.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NY97.
Amino-acid sequence (397 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with B3GNT2?
The strongest Open Targets associations for B3GNT2 are mean corpuscular volume, erythrocyte count, testosterone measurement, Red cell distribution width and ankylosing spondylitis.
How long is the B3GNT2 protein?
The Homo sapiens B3GNT2 protein (UniProt Q9NY97) is 397 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NY97 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NY97 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.