Gamma-2-syntrophin (SNTG2)
Homo sapiens — UniProt Q9NY99
Data last refreshed: (UniProt release unknown)
Key facts
Gamma-2-syntrophin (SNTG2) is a protein from Homo sapiens identified by UniProt accession Q9NY99, 539 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q9NY99; gene symbol SNTG2.
- Organism: Homo sapiens.
- Length: 539 amino acids.
- Top disease associations (Open Targets): body mass index, Myopia and pathological myopia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Gamma-2-syntrophin |
|---|---|
| UniProt accession | Q9NY99 |
| Gene | SNTG2 |
| Organism | Homo sapiens |
| Length | 539 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- body mass index · score 0.31
- Myopia · score 0.11
- pathological myopia · score 0.11
- gastric carcinoma · score 0.02
- schizophrenia · score 0.01
- lung adenocarcinoma · score 0.01
- bipolar disorder · score 0.01
- colorectal cancer · score 0.01
- dyslexia · score 0.01
- Autism · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NY99-F1 | alphafold | PREDICTED | 79.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NY99.
Amino-acid sequence (539 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNTG2?
The strongest Open Targets associations for SNTG2 are body mass index, Myopia, pathological myopia, gastric carcinoma and schizophrenia.
How long is the SNTG2 protein?
The Homo sapiens SNTG2 protein (UniProt Q9NY99) is 539 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NY99 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NY99 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.