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Solute carrier organic anion transporter family member 1C1 (SLCO1C1)

Homo sapiens — UniProt Q9NYB5

Gene: SLCO1C1Homo sapiensSwissProt reviewedTransporter

Data last refreshed: (UniProt release unknown)

Key facts

Solute carrier organic anion transporter family member 1C1 (SLCO1C1) is a protein from Homo sapiens identified by UniProt accession Q9NYB5, 712 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.

  • UniProt accession: Q9NYB5; gene symbol SLCO1C1.
  • Organism: Homo sapiens.
  • Length: 712 amino acids.
  • Target class: Transporter.
  • Top disease associations (Open Targets): body height, bilirubin measurement and BMI-adjusted waist circumference.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSolute carrier organic anion transporter family member 1C1
UniProt accessionQ9NYB5
GeneSLCO1C1
OrganismHomo sapiens
Length712 residues
Molecular weight—
EC numbers—
Target classTransporter (inferred from UniProt keywords / EC)
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (56)

Diseases linked to this target (Open Targets).

  • body height · score 0.46
  • bilirubin measurement · score 0.44
  • BMI-adjusted waist circumference · score 0.26
  • appendicular lean mass · score 0.23
  • cutaneous melanoma · score 0.22
  • sitting height measurement · score 0.20
  • insulin like growth factor measurement · score 0.18
  • cortical surface area measurement · score 0.17
  • forced expiratory volume · score 0.15
  • vital capacity · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NYB5-F1alphafoldPREDICTED78.47—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYB5.

Amino-acid sequence (712 residues)

MDTSSKENIQ LFCKTSVQPV GRPSFKTEYP SSEEKQPCCG ELKVFLCALS FVYFAKALAE GYLKSTITQI ERRFDIPSSL VGVIDGSFEI GNLLVITFVS YFGAKLHRPK IIGAGCVIMG VGTLLIAMPQ FFMEQYKYER YSPSSNSTLS ISPCLLESSS QLPVSVMEKS KSKISNECEV DTSSSMWIYV FLGNLLRGIG ETPIQPLGIA YLDDFASEDN AAFYIGCVQT VAIIGPIFGF LLGSLCAKLY VDIGFVNLDH ITITPKDPQW VGAWWLGYLI AGIISLLAAV PFWYLPKSLP RSQSREDSNS SSEKSKFIID DHTDYQTPQG ENAKIMEMAR DFLPSLKNLF GNPVYFLYLC TSTVQFNSLF GMVTYKPKYI EQQYGQSSSR ANFVIGLINI PAVALGIFSG GIVMKKFRIS VCGAAKLYLG SSVFGYLLFL SLFALGCENS DVAGLTVSYQ GTKPVSYHER ALFSDCNSRC KCSETKWEPM CGENGITYVS ACLAGCQTSN RSGKNIIFYN CTCVGIAASK SGNSSGIVGR CQKDNGCPQM FLYFLVISVI TSYTLSLGGI PGYILLLRCI KPQLKSFALG IYTLAIRVLA GIPAPVYFGV LIDTSCLKWG FKRCGSRGSC RLYDSNVFRH IYLGLTVILG TVSILLSIAV LFILKKNYVS KHRSFITKRE RTMVSTRFQK ENYTTSDHLL QPNYWPGKET QL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SLCO1C1?

The strongest Open Targets associations for SLCO1C1 are body height, bilirubin measurement, BMI-adjusted waist circumference, appendicular lean mass and cutaneous melanoma.

How long is the SLCO1C1 protein?

The Homo sapiens SLCO1C1 protein (UniProt Q9NYB5) is 712 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NYB5
GeneSLCO1C1
OrganismHomo sapiens
Length712
Binders0
Diseases56
View on UniProt