Homeobox protein Hox-C10 (HOXC10)
Homo sapiens — UniProt Q9NYD6
Data last refreshed: (UniProt release unknown)
Key facts
Homeobox protein Hox-C10 (HOXC10) is a protein from Homo sapiens identified by UniProt accession Q9NYD6, 342 residues long. MolForge cross-references it against 0 known binders and 344 disease associations.
- UniProt accession: Q9NYD6; gene symbol HOXC10.
- Organism: Homo sapiens.
- Length: 342 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cancer and hepatocellular carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Homeobox protein Hox-C10 |
|---|---|
| UniProt accession | Q9NYD6 |
| Gene | HOXC10 |
| Organism | Homo sapiens |
| Length | 342 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (344)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.28
- cancer · score 0.10
- hepatocellular carcinoma · score 0.09
- esophageal squamous cell carcinoma · score 0.09
- non-small cell lung carcinoma · score 0.08
- head and neck squamous cell carcinoma · score 0.08
- oral squamous cell carcinoma · score 0.08
- osteosarcoma · score 0.08
- breast cancer · score 0.08
- lung adenocarcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYD6-F1 | alphafold | PREDICTED | 59.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYD6.
Amino-acid sequence (342 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HOXC10?
The strongest Open Targets associations for HOXC10 are neurodegenerative disease, cancer, hepatocellular carcinoma, esophageal squamous cell carcinoma and non-small cell lung carcinoma.
How long is the HOXC10 protein?
The Homo sapiens HOXC10 protein (UniProt Q9NYD6) is 342 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYD6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYD6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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