Protein FAM53C (FAM53C)
Homo sapiens — UniProt Q9NYF3
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM53C (FAM53C) is a protein from Homo sapiens identified by UniProt accession Q9NYF3, 392 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q9NYF3; gene symbol FAM53C.
- Organism: Homo sapiens.
- Length: 392 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, schizophrenia and bipolar disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM53C |
|---|---|
| UniProt accession | Q9NYF3 |
| Gene | FAM53C |
| Organism | Homo sapiens |
| Length | 392 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- schizophrenia · score 0.14
- bipolar disorder · score 0.12
- obsessive-compulsive disorder · score 0.09
- attention deficit hyperactivity disorder · score 0.09
- autism spectrum disorder · score 0.09
- Tourette syndrome · score 0.09
- unipolar depression · score 0.09
- anorexia nervosa · score 0.09
- bipolar I disorder · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYF3-F1 | alphafold | PREDICTED | 52.12 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYF3.
Amino-acid sequence (392 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM53C?
The strongest Open Targets associations for FAM53C are neurodegenerative disease, schizophrenia, bipolar disorder, obsessive-compulsive disorder and attention deficit hyperactivity disorder.
How long is the FAM53C protein?
The Homo sapiens FAM53C protein (UniProt Q9NYF3) is 392 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYF3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYF3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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