Palmitoyltransferase ZDHHC3 (ZDHHC3)
Homo sapiens — UniProt Q9NYG2
Data last refreshed: (UniProt release unknown)
Key facts
Palmitoyltransferase ZDHHC3 (ZDHHC3) is a protein from Homo sapiens identified by UniProt accession Q9NYG2, 299 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.
- UniProt accession: Q9NYG2; gene symbol ZDHHC3.
- Organism: Homo sapiens.
- Length: 299 amino acids.
- Top disease associations (Open Targets): COVID-19, PHF-tau measurement and t-tau:beta-amyloid 1-42 ratio measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Palmitoyltransferase ZDHHC3 |
|---|---|
| UniProt accession | Q9NYG2 |
| Gene | ZDHHC3 |
| Organism | Homo sapiens |
| Length | 299 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- COVID-19 · score 0.37
- PHF-tau measurement · score 0.12
- t-tau:beta-amyloid 1-42 ratio measurement · score 0.10
- neoplasm · score 0.08
- pancreatic neoplasm · score 0.08
- non-alcoholic steatohepatitis · score 0.07
- cancer · score 0.06
- pancreatic adenocarcinoma · score 0.06
- attention deficit hyperactivity disorder · score 0.04
- cardiomyopathy · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYG2-F1 | alphafold | PREDICTED | 85.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYG2.
Amino-acid sequence (299 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZDHHC3?
The strongest Open Targets associations for ZDHHC3 are COVID-19, PHF-tau measurement, t-tau:beta-amyloid 1-42 ratio measurement, neoplasm and pancreatic neoplasm.
How long is the ZDHHC3 protein?
The Homo sapiens ZDHHC3 protein (UniProt Q9NYG2) is 299 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYG2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYG2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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