Anaphase-promoting complex subunit 11 (ANAPC11)
Homo sapiens — UniProt Q9NYG5
Data last refreshed: (UniProt release unknown)
Key facts
Anaphase-promoting complex subunit 11 (ANAPC11) is a protein from Homo sapiens identified by UniProt accession Q9NYG5, 84 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q9NYG5; gene symbol ANAPC11.
- Organism: Homo sapiens.
- Length: 84 amino acids.
- Top disease associations (Open Targets): lung adenocarcinoma, clear cell renal carcinoma and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Anaphase-promoting complex subunit 11 |
|---|---|
| UniProt accession | Q9NYG5 |
| Gene | ANAPC11 |
| Organism | Homo sapiens |
| Length | 84 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- cancer · score 0.02
- neoplasm · score 0.01
- squamous cell lung carcinoma · score 0.01
- non-small cell lung carcinoma · score 0.01
- bladder transitional cell carcinoma · score 0.01
- glioblastoma multiforme · score 0.01
- colorectal neoplasm · score 0.01
- Myocardial Ischemia · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYG5-F1 | alphafold | PREDICTED | 92.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYG5.
Amino-acid sequence (84 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANAPC11?
The strongest Open Targets associations for ANAPC11 are lung adenocarcinoma, clear cell renal carcinoma, cancer, neoplasm and squamous cell lung carcinoma.
How long is the ANAPC11 protein?
The Homo sapiens ANAPC11 protein (UniProt Q9NYG5) is 84 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYG5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYG5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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