PH and SEC7 domain-containing protein 3 (PSD3)
Homo sapiens — UniProt Q9NYI0
Data last refreshed: (UniProt release unknown)
Key facts
PH and SEC7 domain-containing protein 3 (PSD3) is a protein from Homo sapiens identified by UniProt accession Q9NYI0, 1048 residues long. MolForge cross-references it against 0 known binders and 144 disease associations.
- UniProt accession: Q9NYI0; gene symbol PSD3.
- Organism: Homo sapiens.
- Length: 1048 amino acids.
- Top disease associations (Open Targets): mean platelet volume, platelet count and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PH and SEC7 domain-containing protein 3 |
|---|---|
| UniProt accession | Q9NYI0 |
| Gene | PSD3 |
| Organism | Homo sapiens |
| Length | 1048 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (144)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.43
- platelet count · score 0.40
- lymphocyte count · score 0.33
- heel bone mineral density · score 0.27
- urate measurement · score 0.27
- PHF-tau measurement · score 0.26
- protein measurement · score 0.25
- schizophrenia · score 0.22
- insulin measurement · score 0.14
- platelet component distribution width · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYI0-F1 | alphafold | PREDICTED | 54.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYI0.
Amino-acid sequence (1048 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PSD3?
The strongest Open Targets associations for PSD3 are mean platelet volume, platelet count, lymphocyte count, heel bone mineral density and urate measurement.
How long is the PSD3 protein?
The Homo sapiens PSD3 protein (UniProt Q9NYI0) is 1048 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYI0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYI0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.