Peptidyl-prolyl cis-trans isomerase FKBP11 (FKBP11)
Homo sapiens — UniProt Q9NYL4
Data last refreshed: (UniProt release unknown)
Key facts
Peptidyl-prolyl cis-trans isomerase FKBP11 (FKBP11) is a protein from Homo sapiens identified by UniProt accession Q9NYL4, 201 residues long. MolForge cross-references it against 0 known binders and 92 disease associations.
- UniProt accession: Q9NYL4; gene symbol FKBP11.
- Organism: Homo sapiens.
- Length: 201 amino acids.
- Top disease associations (Open Targets): nonpapillary renal cell carcinoma, hepatocellular carcinoma and immature platelet fraction.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Peptidyl-prolyl cis-trans isomerase FKBP11 |
|---|---|
| UniProt accession | Q9NYL4 |
| Gene | FKBP11 |
| Organism | Homo sapiens |
| Length | 201 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (92)
Diseases linked to this target (Open Targets).
- nonpapillary renal cell carcinoma · score 0.05
- hepatocellular carcinoma · score 0.05
- immature platelet fraction · score 0.05
- Systemic lupus erythematosus · score 0.04
- body height · score 0.04
- dacryocystitis-osteopoikilosis syndrome · score 0.04
- metabolite measurement · score 0.04
- melorheostosis · score 0.04
- gnathodiaphyseal dysplasia · score 0.04
- immunodeficiency 75 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYL4-F1 | alphafold | PREDICTED | 87.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYL4.
Amino-acid sequence (201 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FKBP11?
The strongest Open Targets associations for FKBP11 are nonpapillary renal cell carcinoma, hepatocellular carcinoma, immature platelet fraction, Systemic lupus erythematosus and body height.
How long is the FKBP11 protein?
The Homo sapiens FKBP11 protein (UniProt Q9NYL4) is 201 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYL4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYL4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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