Tropomodulin-3 (TMOD3)
Homo sapiens — UniProt Q9NYL9
Data last refreshed: (UniProt release unknown)
Key facts
Tropomodulin-3 (TMOD3) is a protein from Homo sapiens identified by UniProt accession Q9NYL9, 352 residues long. MolForge cross-references it against 0 known binders and 112 disease associations.
- UniProt accession: Q9NYL9; gene symbol TMOD3.
- Organism: Homo sapiens.
- Length: 352 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, frailty measurement and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tropomodulin-3 |
|---|---|
| UniProt accession | Q9NYL9 |
| Gene | TMOD3 |
| Organism | Homo sapiens |
| Length | 352 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (112)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.23
- frailty measurement · score 0.21
- body mass index · score 0.21
- cortical surface area measurement · score 0.20
- lung adenocarcinoma · score 0.19
- ovarian cancer · score 0.18
- glioblastoma multiforme · score 0.18
- brain measurement · score 0.15
- body height · score 0.13
- endometrial cancer · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYL9-F1 | alphafold | PREDICTED | 82.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYL9.
Amino-acid sequence (352 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMOD3?
The strongest Open Targets associations for TMOD3 are breast adenocarcinoma, frailty measurement, body mass index, cortical surface area measurement and lung adenocarcinoma.
How long is the TMOD3 protein?
The Homo sapiens TMOD3 protein (UniProt Q9NYL9) is 352 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYL9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYL9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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