G-protein coupled receptor 83 (GPR83)
Homo sapiens — UniProt Q9NYM4
Data last refreshed: (UniProt release unknown)
Key facts
G-protein coupled receptor 83 (GPR83) is a protein from Homo sapiens identified by UniProt accession Q9NYM4, 423 residues long. MolForge cross-references it against 0 known binders and 92 disease associations.
- UniProt accession: Q9NYM4; gene symbol GPR83.
- Organism: Homo sapiens.
- Length: 423 amino acids.
- Top disease associations (Open Targets): testosterone measurement, age at menarche and sleep apnea measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | G-protein coupled receptor 83 |
|---|---|
| UniProt accession | Q9NYM4 |
| Gene | GPR83 |
| Organism | Homo sapiens |
| Length | 423 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (92)
Diseases linked to this target (Open Targets).
- testosterone measurement · score 0.43
- age at menarche · score 0.24
- sleep apnea measurement · score 0.11
- obstructive sleep apnea · score 0.11
- anxiety · score 0.08
- attention deficit hyperactivity disorder · score 0.08
- attention deficit-hyperactivity disorder 8 · score 0.06
- Tourette syndrome · score 0.06
- Potocki-Lupski syndrome · score 0.05
- autism · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYM4-F1 | alphafold | PREDICTED | 76.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYM4.
Amino-acid sequence (423 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GPR83?
The strongest Open Targets associations for GPR83 are testosterone measurement, age at menarche, sleep apnea measurement, obstructive sleep apnea and anxiety.
How long is the GPR83 protein?
The Homo sapiens GPR83 protein (UniProt Q9NYM4) is 423 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYM4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYM4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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