Ras-like protein family member 12 (RASL12)
Homo sapiens — UniProt Q9NYN1
Data last refreshed: (UniProt release unknown)
Key facts
Ras-like protein family member 12 (RASL12) is a protein from Homo sapiens identified by UniProt accession Q9NYN1, 266 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q9NYN1; gene symbol RASL12.
- Organism: Homo sapiens.
- Length: 266 amino acids.
- Top disease associations (Open Targets): white matter hyperintensity measurement, FEV/FVC ratio and environmental tobacco smoke exposure measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras-like protein family member 12 |
|---|---|
| UniProt accession | Q9NYN1 |
| Gene | RASL12 |
| Organism | Homo sapiens |
| Length | 266 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- white matter hyperintensity measurement · score 0.16
- FEV/FVC ratio · score 0.09
- environmental tobacco smoke exposure measurement · score 0.09
- lung adenocarcinoma · score 0.02
- neoplasm · score 0.02
- endometrial carcinoma · score 0.02
- non-small cell lung carcinoma · score 0.01
- colorectal cancer · score 0.01
- breast carcinoma · score 0.01
- Persistent Müllerian duct syndrome · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYN1-F1 | alphafold | PREDICTED | 78.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYN1.
Amino-acid sequence (266 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RASL12?
The strongest Open Targets associations for RASL12 are white matter hyperintensity measurement, FEV/FVC ratio, environmental tobacco smoke exposure measurement, lung adenocarcinoma and neoplasm.
How long is the RASL12 protein?
The Homo sapiens RASL12 protein (UniProt Q9NYN1) is 266 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYN1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYN1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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