Very long chain fatty acid elongase 5 (ELOVL5)
Homo sapiens — UniProt Q9NYP7
Data last refreshed: (UniProt release unknown)
Key facts
Very long chain fatty acid elongase 5 (ELOVL5) is a protein from Homo sapiens identified by UniProt accession Q9NYP7, 299 residues long. MolForge cross-references it against 0 known binders and 157 disease associations.
- UniProt accession: Q9NYP7; gene symbol ELOVL5.
- Organism: Homo sapiens.
- Length: 299 amino acids.
- Top disease associations (Open Targets): Spinocerebellar ataxia type 38, neurodegenerative disease and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Very long chain fatty acid elongase 5 |
|---|---|
| UniProt accession | Q9NYP7 |
| Gene | ELOVL5 |
| Organism | Homo sapiens |
| Length | 299 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (157)
Diseases linked to this target (Open Targets).
- Spinocerebellar ataxia type 38 · score 0.69
- neurodegenerative disease · score 0.52
- lymphocyte count · score 0.47
- mean platelet volume · score 0.46
- Red cell distribution width · score 0.44
- mean reticulocyte volume · score 0.40
- lymphocyte percentage of leukocytes · score 0.36
- colorectal cancer · score 0.35
- metastasis measurement · score 0.35
- survival time · score 0.35
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYP7-F1 | alphafold | PREDICTED | 81.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYP7.
Amino-acid sequence (299 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ELOVL5?
The strongest Open Targets associations for ELOVL5 are Spinocerebellar ataxia type 38, neurodegenerative disease, lymphocyte count, mean platelet volume and Red cell distribution width.
How long is the ELOVL5 protein?
The Homo sapiens ELOVL5 protein (UniProt Q9NYP7) is 299 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYP7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYP7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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