Exosomal polycystin-1-interacting protein (EPCIP)
Homo sapiens — UniProt Q9NYP8
Data last refreshed: (UniProt release unknown)
Key facts
Exosomal polycystin-1-interacting protein (EPCIP) is a protein from Homo sapiens identified by UniProt accession Q9NYP8, 219 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q9NYP8; gene symbol EPCIP.
- Organism: Homo sapiens.
- Length: 219 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, gastroesophageal reflux disease and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Exosomal polycystin-1-interacting protein |
|---|---|
| UniProt accession | Q9NYP8 |
| Gene | EPCIP |
| Organism | Homo sapiens |
| Length | 219 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.34
- gastroesophageal reflux disease · score 0.30
- body mass index · score 0.23
- cortical surface area measurement · score 0.22
- autosomal recessive spondylocostal dysostosis · score 0.07
- cortical thickness · score 0.06
- cervical spondylosis · score 0.05
- Prata-Liberal-Goncalves syndrome · score 0.04
- central nervous system cancer · score 0.04
- osteomesopyknosis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYP8-F1 | alphafold | PREDICTED | 76.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYP8.
Amino-acid sequence (219 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EPCIP?
The strongest Open Targets associations for EPCIP are self reported educational attainment, gastroesophageal reflux disease, body mass index, cortical surface area measurement and autosomal recessive spondylocostal dysostosis.
How long is the EPCIP protein?
The Homo sapiens EPCIP protein (UniProt Q9NYP8) is 219 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYP8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYP8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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