2-Hydroxyacid oxidase 2 (HAO2)
Homo sapiens — UniProt Q9NYQ3
Data last refreshed: (UniProt release unknown)
Key facts
2-Hydroxyacid oxidase 2 (HAO2) is a protein from Homo sapiens identified by UniProt accession Q9NYQ3, 351 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.
- UniProt accession: Q9NYQ3; gene symbol HAO2.
- Organism: Homo sapiens.
- Length: 351 amino acids.
- Top disease associations (Open Targets): serum metabolite measurement, outer ear morphology trait and antitragus size.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | 2-Hydroxyacid oxidase 2 |
|---|---|
| UniProt accession | Q9NYQ3 |
| Gene | HAO2 |
| Organism | Homo sapiens |
| Length | 351 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (52)
Diseases linked to this target (Open Targets).
- serum metabolite measurement · score 0.44
- outer ear morphology trait · score 0.28
- antitragus size · score 0.28
- folding of antihelix · score 0.28
- balding measurement · score 0.25
- cortical surface area measurement · score 0.24
- osteoarthritis · score 0.24
- lobe attachment · score 0.24
- lower face morphology measurement · score 0.24
- blood protein measurement · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYQ3-F1 | alphafold | PREDICTED | 93.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYQ3.
Amino-acid sequence (351 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HAO2?
The strongest Open Targets associations for HAO2 are serum metabolite measurement, outer ear morphology trait, antitragus size, folding of antihelix and balding measurement.
How long is the HAO2 protein?
The Homo sapiens HAO2 protein (UniProt Q9NYQ3) is 351 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYQ3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYQ3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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