WD repeat and SOCS box-containing protein 2 (WSB2)
Homo sapiens — UniProt Q9NYS7
Data last refreshed: (UniProt release unknown)
Key facts
WD repeat and SOCS box-containing protein 2 (WSB2) is a protein from Homo sapiens identified by UniProt accession Q9NYS7, 404 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9NYS7; gene symbol WSB2.
- Organism: Homo sapiens.
- Length: 404 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, erythrocyte count and red blood cell density measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WD repeat and SOCS box-containing protein 2 |
|---|---|
| UniProt accession | Q9NYS7 |
| Gene | WSB2 |
| Organism | Homo sapiens |
| Length | 404 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- erythrocyte count · score 0.28
- red blood cell density measurement · score 0.28
- hepatocellular carcinoma · score 0.07
- monocyte count · score 0.04
- melanoma · score 0.04
- neoplasm · score 0.04
- tooth agenesis · score 0.03
- alcohol consumption measurement · score 0.02
- childhood trauma measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYS7-F1 | alphafold | PREDICTED | 84.90 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYS7.
Amino-acid sequence (404 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WSB2?
The strongest Open Targets associations for WSB2 are neurodegenerative disease, erythrocyte count, red blood cell density measurement, hepatocellular carcinoma and monocyte count.
How long is the WSB2 protein?
The Homo sapiens WSB2 protein (UniProt Q9NYS7) is 404 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYS7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYS7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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