Zinc finger protein 226 (ZNF226)
Homo sapiens — UniProt Q9NYT6
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 226 (ZNF226) is a protein from Homo sapiens identified by UniProt accession Q9NYT6, 803 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q9NYT6; gene symbol ZNF226.
- Organism: Homo sapiens.
- Length: 803 amino acids.
- Top disease associations (Open Targets): C-reactive protein measurement, hypoparathyroidism, familial isolated, 2 and Testicular regression syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 226 |
|---|---|
| UniProt accession | Q9NYT6 |
| Gene | ZNF226 |
| Organism | Homo sapiens |
| Length | 803 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- C-reactive protein measurement · score 0.10
- hypoparathyroidism, familial isolated, 2 · score 0.04
- Testicular regression syndrome · score 0.04
- Primary hypomagnesemia with secondary hypocalcemia · score 0.04
- 46,XX ovotesticular disorder of sex development · score 0.04
- 46,XY complete gonadal dysgenesis · score 0.04
- Familial isolated hypoparathyroidism · score 0.04
- blue diaper syndrome · score 0.04
- testicular agenesis · score 0.04
- adamantinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYT6-F1 | alphafold | PREDICTED | 65.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYT6.
Amino-acid sequence (803 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF226?
The strongest Open Targets associations for ZNF226 are C-reactive protein measurement, hypoparathyroidism, familial isolated, 2, Testicular regression syndrome, Primary hypomagnesemia with secondary hypocalcemia and 46,XX ovotesticular disorder of sex development.
How long is the ZNF226 protein?
The Homo sapiens ZNF226 protein (UniProt Q9NYT6) is 803 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYT6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYT6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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