UDP-glucose:glycoprotein glucosyltransferase 2 (UGGT2)
Homo sapiens — UniProt Q9NYU1
Data last refreshed: (UniProt release unknown)
Key facts
UDP-glucose:glycoprotein glucosyltransferase 2 (UGGT2) is a protein from Homo sapiens identified by UniProt accession Q9NYU1, 1516 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.
- UniProt accession: Q9NYU1; gene symbol UGGT2.
- Organism: Homo sapiens.
- Length: 1516 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, urate measurement and pancreatic adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | UDP-glucose:glycoprotein glucosyltransferase 2 |
|---|---|
| UniProt accession | Q9NYU1 |
| Gene | UGGT2 |
| Organism | Homo sapiens |
| Length | 1516 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (60)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- urate measurement · score 0.23
- pancreatic adenocarcinoma · score 0.21
- body height · score 0.21
- bone density · score 0.20
- blood urea nitrogen measurement · score 0.18
- leukocyte count · score 0.17
- FEV/FVC ratio · score 0.08
- appendicular lean mass · score 0.07
- femoral neck fracture · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYU1-F1 | alphafold | PREDICTED | 85.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYU1.
Amino-acid sequence (1516 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UGGT2?
The strongest Open Targets associations for UGGT2 are neurodegenerative disease, urate measurement, pancreatic adenocarcinoma, body height and bone density.
How long is the UGGT2 protein?
The Homo sapiens UGGT2 protein (UniProt Q9NYU1) is 1516 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYU1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYU1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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