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Taste receptor type 2 member 16 (TAS2R16)

Homo sapiens — UniProt Q9NYV7

Gene: TAS2R16Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Taste receptor type 2 member 16 (TAS2R16) is a protein from Homo sapiens identified by UniProt accession Q9NYV7, 291 residues long. MolForge cross-references it against 1 known binders and 32 disease associations.

  • UniProt accession: Q9NYV7; gene symbol TAS2R16.
  • Organism: Homo sapiens.
  • Length: 291 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, glioblastoma multiforme and lung adenocarcinoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameTaste receptor type 2 member 16
UniProt accessionQ9NYV7
GeneTAS2R16
OrganismHomo sapiens
Length291 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (32)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.27
  • glioblastoma multiforme · score 0.23
  • lung adenocarcinoma · score 0.18
  • ovarian cancer · score 0.18
  • breast adenocarcinoma · score 0.16
  • squamous cell lung carcinoma · score 0.13
  • head and neck squamous cell carcinoma · score 0.13
  • gastric adenocarcinoma · score 0.10
  • low grade glioma · score 0.10
  • protein measurement · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NYV7-F1alphafoldPREDICTED82.51—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYV7.

Amino-acid sequence (291 residues)

MIPIQLTVFF MIIYVLESLT IIVQSSLIVA VLGREWLQVR RLMPVDMILI SLGISRFCLQ WASMLNNFCS YFNLNYVLCN LTITWEFFNI LTFWLNSLLT VFYCIKVSSF THHIFLWLRW RILRLFPWIL LGSLMITCVT IIPSAIGNYI QIQLLTMEHL PRNSTVTDKL ENFHQYQFQA HTVALVIPFI LFLASTIFLM ASLTKQIQHH STGHCNPSMK ARFTALRSLA VLFIVFTSYF LTILITIIGT LFDKRCWLWV WEAFVYAFIL MHSTSLMLSS PTLKRILKGK C

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with TAS2R16?

The strongest Open Targets associations for TAS2R16 are neurodegenerative disease, glioblastoma multiforme, lung adenocarcinoma, ovarian cancer and breast adenocarcinoma.

How long is the TAS2R16 protein?

The Homo sapiens TAS2R16 protein (UniProt Q9NYV7) is 291 amino acids long.

Browse: Targets: T · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NYV7
GeneTAS2R16
OrganismHomo sapiens
Length291
Binders1
Diseases32
View on UniProt