Taste receptor type 2 member 13 (TAS2R13)
Homo sapiens — UniProt Q9NYV9
Data last refreshed: (UniProt release unknown)
Key facts
Taste receptor type 2 member 13 (TAS2R13) is a protein from Homo sapiens identified by UniProt accession Q9NYV9, 303 residues long. MolForge cross-references it against 1 known binders and 17 disease associations.
- UniProt accession: Q9NYV9; gene symbol TAS2R13.
- Organism: Homo sapiens.
- Length: 303 amino acids.
- Top disease associations (Open Targets): lung adenocarcinoma, breast adenocarcinoma and head and neck squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Taste receptor type 2 member 13 |
|---|---|
| UniProt accession | Q9NYV9 |
| Gene | TAS2R13 |
| Organism | Homo sapiens |
| Length | 303 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.16
- head and neck squamous cell carcinoma · score 0.13
- gastric adenocarcinoma · score 0.10
- actinic keratosis · score 0.06
- pigmented nodular adrenocortical disease, primary, 3 · score 0.05
- squamous cell carcinoma · score 0.05
- sebaceous of Jadassohn nevus · score 0.05
- breast carcinoma · score 0.05
- congenital adrenal hyperplasia due to cytochrome P450 oxidoreductase deficiency · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYV9-F1 | alphafold | PREDICTED | 88.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYV9.
Amino-acid sequence (303 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TAS2R13?
The strongest Open Targets associations for TAS2R13 are lung adenocarcinoma, breast adenocarcinoma, head and neck squamous cell carcinoma, gastric adenocarcinoma and actinic keratosis.
How long is the TAS2R13 protein?
The Homo sapiens TAS2R13 protein (UniProt Q9NYV9) is 303 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYV9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYV9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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