Taste receptor type 2 member 10 (TAS2R10)
Homo sapiens — UniProt Q9NYW0
Data last refreshed: (UniProt release unknown)
Key facts
Taste receptor type 2 member 10 (TAS2R10) is a protein from Homo sapiens identified by UniProt accession Q9NYW0, 307 residues long. MolForge cross-references it against 3 known binders and 41 disease associations.
- UniProt accession: Q9NYW0; gene symbol TAS2R10.
- Organism: Homo sapiens.
- Length: 307 amino acids.
- Approved drugs acting on it (DrugCentral): Bergapten.
- Top disease associations (Open Targets): glioblastoma multiforme, breast adenocarcinoma and squamous cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Taste receptor type 2 member 10 |
|---|---|
| UniProt accession | Q9NYW0 |
| Gene | TAS2R10 |
| Organism | Homo sapiens |
| Length | 307 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). Approved drug exists
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Approved drugs acting on this target (1)
Approved drugs whose DrugCentral mechanism of action is this protein, most potent first.
Disease associations (41)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.22
- breast adenocarcinoma · score 0.16
- squamous cell lung carcinoma · score 0.13
- head and neck squamous cell carcinoma · score 0.13
- neuroblastoma · score 0.12
- gastric adenocarcinoma · score 0.10
- infectious disease · score 0.02
- neoplasm · score 0.02
- pancreatic neoplasm · score 0.01
- Obesity · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYW0-F1 | alphafold | PREDICTED | 87.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYW0.
Amino-acid sequence (307 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which approved drugs target TAS2R10?
DrugCentral lists 1 approved drug whose mechanism of action is TAS2R10: Bergapten.
Which diseases are associated with TAS2R10?
The strongest Open Targets associations for TAS2R10 are glioblastoma multiforme, breast adenocarcinoma, squamous cell lung carcinoma, head and neck squamous cell carcinoma and neuroblastoma.
How long is the TAS2R10 protein?
The Homo sapiens TAS2R10 protein (UniProt Q9NYW0) is 307 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYW0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYW0 — predicted 3D structure (CC BY 4.0)
- DrugCentral — approved drugs and mechanism-of-action links (CC BY-SA 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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