Taste receptor type 2 member 7 (TAS2R7)
Homo sapiens — UniProt Q9NYW3
Data last refreshed: (UniProt release unknown)
Key facts
Taste receptor type 2 member 7 (TAS2R7) is a protein from Homo sapiens identified by UniProt accession Q9NYW3, 318 residues long. MolForge cross-references it against 1 known binders and 12 disease associations.
- UniProt accession: Q9NYW3; gene symbol TAS2R7.
- Organism: Homo sapiens.
- Length: 318 amino acids.
- Top disease associations (Open Targets): thyroid gland adenocarcinoma, squamous cell lung carcinoma and head and neck squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Taste receptor type 2 member 7 |
|---|---|
| UniProt accession | Q9NYW3 |
| Gene | TAS2R7 |
| Organism | Homo sapiens |
| Length | 318 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.16
- squamous cell lung carcinoma · score 0.13
- head and neck squamous cell carcinoma · score 0.13
- gastric adenocarcinoma · score 0.10
- TSH-secreting pituitary adenoma · score 0.02
- Pituitary prolactin cell adenoma · score 0.00
- Pituitary Gland Adenoma · score 0.00
- type 2 diabetes mellitus · score 0.00
- oral squamous cell carcinoma · score 0.00
- embryonal carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYW3-F1 | alphafold | PREDICTED | 84.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYW3.
Amino-acid sequence (318 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TAS2R7?
The strongest Open Targets associations for TAS2R7 are thyroid gland adenocarcinoma, squamous cell lung carcinoma, head and neck squamous cell carcinoma, gastric adenocarcinoma and TSH-secreting pituitary adenoma.
How long is the TAS2R7 protein?
The Homo sapiens TAS2R7 protein (UniProt Q9NYW3) is 318 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYW3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYW3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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