Taste receptor type 2 member 5 (TAS2R5)
Homo sapiens — UniProt Q9NYW4
Data last refreshed: (UniProt release unknown)
Key facts
Taste receptor type 2 member 5 (TAS2R5) is a protein from Homo sapiens identified by UniProt accession Q9NYW4, 299 residues long. MolForge cross-references it against 1 known binders and 17 disease associations.
- UniProt accession: Q9NYW4; gene symbol TAS2R5.
- Organism: Homo sapiens.
- Length: 299 amino acids.
- Top disease associations (Open Targets): glioblastoma multiforme, breast adenocarcinoma and squamous cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Taste receptor type 2 member 5 |
|---|---|
| UniProt accession | Q9NYW4 |
| Gene | TAS2R5 |
| Organism | Homo sapiens |
| Length | 299 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.22
- breast adenocarcinoma · score 0.16
- squamous cell lung carcinoma · score 0.13
- venous thromboembolism · score 0.10
- sensory perception of bitter taste · score 0.07
- colorectal adenocarcinoma · score 0.04
- body mass index · score 0.02
- neoplasm · score 0.01
- acute myeloid leukemia by FAB classification · score 0.00
- esophageal adenocarcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYW4-F1 | alphafold | PREDICTED | 80.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYW4.
Amino-acid sequence (299 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TAS2R5?
The strongest Open Targets associations for TAS2R5 are glioblastoma multiforme, breast adenocarcinoma, squamous cell lung carcinoma, venous thromboembolism and sensory perception of bitter taste.
How long is the TAS2R5 protein?
The Homo sapiens TAS2R5 protein (UniProt Q9NYW4) is 299 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYW4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYW4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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