Taste receptor type 2 member 3 (TAS2R3)
Homo sapiens — UniProt Q9NYW6
Data last refreshed: (UniProt release unknown)
Key facts
Taste receptor type 2 member 3 (TAS2R3) is a protein from Homo sapiens identified by UniProt accession Q9NYW6, 316 residues long. MolForge cross-references it against 1 known binders and 22 disease associations.
- UniProt accession: Q9NYW6; gene symbol TAS2R3.
- Organism: Homo sapiens.
- Length: 316 amino acids.
- Top disease associations (Open Targets): glioblastoma multiforme, lung adenocarcinoma and squamous cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Taste receptor type 2 member 3 |
|---|---|
| UniProt accession | Q9NYW6 |
| Gene | TAS2R3 |
| Organism | Homo sapiens |
| Length | 316 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.22
- lung adenocarcinoma · score 0.18
- squamous cell lung carcinoma · score 0.13
- head and neck squamous cell carcinoma · score 0.13
- sensory perception of bitter taste · score 0.09
- sebaceous of Jadassohn nevus · score 0.05
- actinic keratosis · score 0.04
- squamous cell carcinoma · score 0.04
- venous thromboembolism · score 0.02
- breast carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYW6-F1 | alphafold | PREDICTED | 87.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYW6.
Amino-acid sequence (316 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TAS2R3?
The strongest Open Targets associations for TAS2R3 are glioblastoma multiforme, lung adenocarcinoma, squamous cell lung carcinoma, head and neck squamous cell carcinoma and sensory perception of bitter taste.
How long is the TAS2R3 protein?
The Homo sapiens TAS2R3 protein (UniProt Q9NYW6) is 316 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYW6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYW6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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