Taste receptor type 2 member 1 (TAS2R1)
Homo sapiens — UniProt Q9NYW7
Data last refreshed: (UniProt release unknown)
Key facts
Taste receptor type 2 member 1 (TAS2R1) is a protein from Homo sapiens identified by UniProt accession Q9NYW7, 299 residues long. MolForge cross-references it against 1 known binders and 23 disease associations.
- UniProt accession: Q9NYW7; gene symbol TAS2R1.
- Organism: Homo sapiens.
- Length: 299 amino acids.
- Top disease associations (Open Targets): rheumatic heart disease, PHF-tau measurement and protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Taste receptor type 2 member 1 |
|---|---|
| UniProt accession | Q9NYW7 |
| Gene | TAS2R1 |
| Organism | Homo sapiens |
| Length | 299 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- rheumatic heart disease · score 0.33
- PHF-tau measurement · score 0.33
- protein measurement · score 0.26
- glioblastoma multiforme · score 0.23
- ovarian cancer · score 0.18
- lung adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.16
- squamous cell lung carcinoma · score 0.13
- medulloblastoma · score 0.13
- head and neck squamous cell carcinoma · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYW7-F1 | alphafold | PREDICTED | 80.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYW7.
Amino-acid sequence (299 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TAS2R1?
The strongest Open Targets associations for TAS2R1 are rheumatic heart disease, PHF-tau measurement, protein measurement, glioblastoma multiforme and ovarian cancer.
How long is the TAS2R1 protein?
The Homo sapiens TAS2R1 protein (UniProt Q9NYW7) is 299 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYW7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYW7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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