RB-associated KRAB zinc finger protein (RBAK)
Homo sapiens — UniProt Q9NYW8
Data last refreshed: (UniProt release unknown)
Key facts
RB-associated KRAB zinc finger protein (RBAK) is a protein from Homo sapiens identified by UniProt accession Q9NYW8, 714 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q9NYW8; gene symbol RBAK.
- Organism: Homo sapiens.
- Length: 714 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cardiac troponin T measurement and protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RB-associated KRAB zinc finger protein |
|---|---|
| UniProt accession | Q9NYW8 |
| Gene | RBAK |
| Organism | Homo sapiens |
| Length | 714 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.29
- cardiac troponin T measurement · score 0.21
- protein measurement · score 0.21
- prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- Familial prostate cancer · score 0.11
- non-small cell lung carcinoma · score 0.08
- DNA methylation · score 0.03
- cancer · score 0.01
- lung adenocarcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYW8-F1 | alphafold | PREDICTED | 66.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYW8.
Amino-acid sequence (714 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RBAK?
The strongest Open Targets associations for RBAK are neurodegenerative disease, cardiac troponin T measurement, protein measurement, prostate cancer and prostate carcinoma.
How long is the RBAK protein?
The Homo sapiens RBAK protein (UniProt Q9NYW8) is 714 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYW8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYW8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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