Neuron-specific vesicular protein calcyon (CALY)
Homo sapiens — UniProt Q9NYX4
Data last refreshed: (UniProt release unknown)
Key facts
Neuron-specific vesicular protein calcyon (CALY) is a protein from Homo sapiens identified by UniProt accession Q9NYX4, 217 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q9NYX4; gene symbol CALY.
- Organism: Homo sapiens.
- Length: 217 amino acids.
- Top disease associations (Open Targets): neuroinflammatory disorder, neurodegenerative disease and glioblastoma multiforme.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Neuron-specific vesicular protein calcyon |
|---|---|
| UniProt accession | Q9NYX4 |
| Gene | CALY |
| Organism | Homo sapiens |
| Length | 217 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- neuroinflammatory disorder · score 0.41
- neurodegenerative disease · score 0.08
- glioblastoma multiforme · score 0.05
- astrocytoma · score 0.04
- medulloblastoma · score 0.04
- atypical teratoid rhabdoid tumor · score 0.03
- central nervous system cancer · score 0.03
- attention deficit hyperactivity disorder · score 0.03
- congenital adrenal hyperplasia · score 0.03
- schizophrenia · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYX4-F1 | alphafold | PREDICTED | 54.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYX4.
Amino-acid sequence (217 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CALY?
The strongest Open Targets associations for CALY are neuroinflammatory disorder, neurodegenerative disease, glioblastoma multiforme, astrocytoma and medulloblastoma.
How long is the CALY protein?
The Homo sapiens CALY protein (UniProt Q9NYX4) is 217 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYX4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYX4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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