Interleukin-20 (IL20)
Homo sapiens — UniProt Q9NYY1
Data last refreshed: (UniProt release unknown)
Key facts
Interleukin-20 (IL20) is a protein from Homo sapiens identified by UniProt accession Q9NYY1, 176 residues long. MolForge cross-references it against 0 known binders and 216 disease associations.
- UniProt accession: Q9NYY1; gene symbol IL20.
- Organism: Homo sapiens.
- Length: 176 amino acids.
- Top disease associations (Open Targets): inflammation, rheumatoid arthritis and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Interleukin-20 |
|---|---|
| UniProt accession | Q9NYY1 |
| Gene | IL20 |
| Organism | Homo sapiens |
| Length | 176 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (216)
Diseases linked to this target (Open Targets).
- inflammation · score 0.11
- rheumatoid arthritis · score 0.11
- neoplasm · score 0.10
- hepatocellular carcinoma · score 0.08
- colitis · score 0.08
- psoriasis · score 0.08
- microphthalmia with limb anomalies · score 0.08
- inflammatory bowel disease · score 0.08
- diabetes mellitus · score 0.08
- Spinal cord injury · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYY1-F1 | alphafold | PREDICTED | 92.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYY1.
Amino-acid sequence (176 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IL20?
The strongest Open Targets associations for IL20 are inflammation, rheumatoid arthritis, neoplasm, hepatocellular carcinoma and colitis.
How long is the IL20 protein?
The Homo sapiens IL20 protein (UniProt Q9NYY1) is 176 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYY1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYY1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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